Of the two, I would definitely go with 10mm. I wrecked my K/L-Frame-sized hands, especially my right hand, in the Eighties, first and worst with a 4” S&W Model 629, then with .41 Magnum Model 58 and 657 sixguns. By about 1990, I accepted that I do not have N-Frame-sized hands, or, more precisely, N-Frame-length fingers. Today, I do not know how much cash it would take, to seriously tempt me to fire even one .44 Mag cartridge, with a Model 329.
Eventually, it came to pass that “Short Frame” big-bore Glocks fit me quite well. Same with the Gen4, with no back-straps pinned onto them. I only have them in .45 ACP, for the present. I know that 10mm is controllable, because I bought an original-version G29, about twenty years ago. It was just a bit too high-volume for my hands, so, I sold it, when I learned that the Short Frames would be introduced.
I know nothing about bear defense, based upon experience, but, here in SE Texas, feral hogs will have us for breakfast. This happened in an adjacent county:
https://abc13.com/christine-rollins-...-hogs/5716849/
Edited to add: On the larger subject, I’ll bet that @
Lost River makes .45 ACP that will ruin a bear’s or hog’s day.