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Thread: COVID-19 vaccines: medical concerns and recommendations

  1. #831
    Member TGS's Avatar
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    Quote Originally Posted by YVK View Post
    The only report that I've seen on this was the CDC piece that was mentioned earlier in the thread. I read it and thought that the quality of data in that report was trash. I remain unclear what has higher rates of myocarditis, covid or mrna.
    When you say "the CDC piece that was mentioned earlier in the thread", are you referring to the post right above yours, posted 3 minutes prior?
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  2. #832
    Deadeye Dick Clusterfrack's Avatar
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    Quote Originally Posted by 0ddl0t View Post
    ...it appears covid19 is about 7 times more likely to cause myocarditis than an mRNA vaccination.

    Of course it might have been other covid19 complications that killed them, but I wouldn't be surprised if covid19 myocarditis tends to be more severe than vaccine myocarditis.
    That's consistent with the information my SME source sent me. His conclusion was that if avoiding myocarditis in young men is the goal, a mRNA vax is the least risky choice.
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  3. #833
    Member Balisong's Avatar
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    Quote Originally Posted by Balisong View Post
    Any input from the medical SMEs here... I want to get the Pfizer booster, but due to air quality and pollen and wind lately, I've been taking once daily Claritin. Any word on if its best to be off of that a while before getting the vaccine?
    Kinda sorta found the answer to my question on the CDC site, I'll post a screenshot
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    Since I only take it when the environment calls for it I think I'll just stop a day or 2 then get the booster

  4. #834
    Quote Originally Posted by TGS View Post
    When you say "the CDC piece that was mentioned earlier in the thread", are you referring to the post right above yours, posted 3 minutes prior?
    No, I wasn't referring to that post but I presume that it is the same data set and it has already been mentioned in this thread earlier

    https://www.cdc.gov/mmwr/volumes/70/wr/mm7035e5.htm
    Doesn't read posts longer than two paragraphs.

  5. #835
    Site Supporter 0ddl0t's Avatar
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    Quote Originally Posted by 0ddl0t View Post
    I haven't seen an age breakdown of myocarditis after covid19
    From YVK's link:

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    vs





    So it would appear Covid19 increases the risk of myocarditis somewhere between 5.5x and 9.2x in 16-24 year-olds while the Pfizer vaccine increases the risk between 4.5x and 17.8x in 16-19 year-old boys and between 3.2x and 11.9x in 20-24 year-old boys.

    Those 95% confidence intervals are huge and we're comparing boys & girls with covid vs boys with the vaccine so we can't say for certain which carries the higher risk, but I'd lean toward covid being the greater risk. Again, myocarditis is a tiny risk overall and young men appear to be the only demographic where it could be close.

  6. #836
    Site Supporter Sensei's Avatar
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    Quote Originally Posted by Clusterfrack View Post
    That's consistent with the information my SME source sent me. His conclusion was that if avoiding myocarditis in young men is the goal, a mRNA vax is the least risky choice.
    We probably need to differentiate between COVID myocarditis and the right heart failure that frequently occurs with prolonged, severe ARDS. Many patients with prolonged ARDS will develop RV dysfunction that is largely mediated by increased pulmonary vascular resistance from the hypoxia, hypercarbia, acidemia, high mean airway pressures on the ventilator, and inflammatory mediators that constrict the pulmonary vasculature. The RV is a thin-walled, weak pus that does not tolerate sudden increases in pressure from increased pulmonary vascular resistance associated with ARDS from any cause.

    Unless these patients are getting cardiac biopsies or cardiac MRIs, this is going to be hard to tease out. I suppose that the timing of symptoms may be a clue in some cases such as heart failure that occurs after recovering from COVID or near the end of an otherwise mild respiratory course.

    This is probably why some of the best COVID outcomes on ECMO are coming out of the groups using a V-PA cannulation approach (Protek Duo) rather than traditional VV ECMO. In VV ECMO, the cannulas drain deoxygenated blood from the vena cava, send it to an oxygenator, and then pumps it back to the right atrium where the oxygenated blood circulates through the poorly functioning lungs that do very little before going back to the left heart to be sent to the rest of the body. This provides some measure of indirect RV support by minimizing hypoxia, hypercarbia, acidemia, and the need for high ventilators pressures. In V-PA cannulation, the blood return catheter tip is advanced into the pulmonary artery and the pump provides direct RV support and functions like an oxygenating right ventricular assist device (RVAD). I’ve got 1 patient with COVID lung destruction (now clear of the virus but horribly trashed lungs) on a Protek and is trach’ed, awake, and participating in bedside physical therapy with a goal of getting a lung transplant before Halloween. Our goal is to protect his right heart as a heart-lung transplant is a bridge too far…
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  7. #837
    Site Supporter Kanye Wyoming's Avatar
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    I just want to take a moment to again thank all the doctors, scientists, and health care folks who have been posting here. In a world where it's often hard to figure out WTF the true story is on any given issue, we are extremely fortunate to have the benefit of your observations and insights.

    Also a big shout out to @0ddl0t. The studies and graphs and charts and all the other good shit you post are often Greek to me, but then you pithily summarize things so that an 8th grader can understand. As one of the many lawyers who went to law school because we were told there would be no math, I'm very appreciative.

  8. #838
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    Quote Originally Posted by Sensei View Post
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  9. #839
    THE THIRST MUTILATOR Nephrology's Avatar
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    Quote Originally Posted by 0ddl0t View Post
    From YVK's link:

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    vs





    So it would appear Covid19 increases the risk of myocarditis somewhere between 5.5x and 9.2x in 16-24 year-olds while the Pfizer vaccine increases the risk between 4.5x and 17.8x in 16-19 year-old boys and between 3.2x and 11.9x in 20-24 year-old boys.

    Those 95% confidence intervals are huge and we're comparing boys & girls with covid vs boys with the vaccine so we can't say for certain which carries the higher risk, but I'd lean toward covid being the greater risk. Again, myocarditis is a tiny risk overall and young men appear to be the only demographic where it could be close.
    I would need to read that study to get more context on the figure as study design is an important lens through which to view results. Will take a look later when my schedule is less terrible and my sleep deficit less promounced.

  10. #840
    Member Risto's Avatar
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    I just popped positive on the binaxnow home test.

    Have been feeling fatigue since Thursday night. Today woke up with headache, congestion, very noticeable joint and body ache, mild diarrhea, and sore throat. No temperature.

    I was vaccinated with Pfizer in March (both doses). I Honestly did not expect to feel this sick when I eventually got exposed.

    Anyhow I’m upping my vitamins and etc:
    -36mg of prescription ivermectin (5days)
    -5000 IU vitD
    -325mg aspirin
    -1000mg vitC
    -Melatonin
    -500 mg quercetin
    -1000 mg zinc

    Hoping for the best!


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