I own 44 Magnums because I like S&W Model 29's and Ruger Flattops.
I own 45 Colts because I like Ruger Bisley's and S&W Model 25's.
Either cartridge will drive a 250-300gr bullet to 1000fps and that is all the power I need, or want, in a revolver cartridge these days, after years of pounding my wrists with heavy recoil.
Buy the gun that makes you happy; whether it is a 44 Magnum or a 45 Colt is largely irrelevant, particularly if you are a hand loader.
Edited to add: I never had extraction issues with my Marlin 1894 in 45 Colt when using Starline brass. Some off-brand brass from gunshow reloads I picked up had very small rims, and those resulted in some failures-to-extract from a dirty chamber in the 1894, but standardizing all my brass to Starline fixed that problem.