This. The good thing about the "FBI" load (or the lesser-known "RCMP" load) is that there is indeed enough track record to make theoretical discussions moot. Short answer: for 2" K-frames, Remington's version has a respectable record in shootings, with the same acknowledgement that we've come a ways down the road in bullet design with regard to intermediate barriers.
The Remmy is my go-to short-barrel load for anything that isn't a lightweight 5-shot. Granted, I'm a very low-speed guy, so grain of salt and all that, but the actual usage stats aren't bad. Shoots pretty much to POA with all my K-frames, too.