There are several types of Point Shooting which is a term used for shooting sans sights.
It differs from Sight Shooting which employs one or both sights and the use of a two handed grip, and which is the fastest and most accurate competition shooting method.
However; studies, the literature, and videos of CQB situations, have established that Sight Shooting does not carry over to close quarters life threat situations.
In most all real defensive life threat Close Quarters shootings, where there is the greatest chance of one being shot and/or killed, Sight Shooting is not used.
The oft heard mantra that you will fight as you train, sounds good and reassuring, but it is just hope, and not reality. If it was true, the hit rate in those situations would not be the recognized and dismal rate of less than 20%.
Blame for the failure of the use of Sight Shooting can be placed on our instinctive "Fight or Flight" response, which science says will kick in automatically in defensive life threat situations, and cause physiological changes such as the loss of near vision which is needed for focusing on the sights.
The dynamics of CQB, and time and environmental constraints such as bad lighting, can prevent the use of Sight Shooting. And strong hand only shooting is used in most all cases. Also, a crush grip will be used in CQB which will result in low left shooting with autoloaders.
Blame is due to those who fail to recognize and deal with these and other constraints on its use.
So, if you have a gun for self defense, and you are not a SEAL or a super gun operator training 24/7 or close to it, it makes sense to know about and become proficient in some type of Point Shooting, as that is what you will default to, when someone is trying to kill you at CQ.
Here are links to Wikipedia articles on Point Shooting with links to sources:
Point Shooting
http://en.wikipedia.org/wiki/Point_shooting
Center Axis Relock
http://en.wikipedia.org/wiki/Center_Axis_Relock