I think you misconstrued what @WobblyPossum meant when he referenced reloaded cases. I tend to agree with the consensus that the 'Signade' phenomenon is related to reloaded (as in fired/resized/new powder and bullet on a reloading press) ammo, where the case wall has been thinned out, and slightly less case support in the 320 barrel design than in other pistols.
Repeatedly reloading a chambered round into a gun will not thin out the case wall, but can result in bullet setback, which is a different issue.