Talking about basic practice ammo, not benchrest precison or anything.
I have handloaded but not much, and its been many years for multiple reasons but looking at getting serious just to extent of couple hundred rounds of practice ammo a year each for 38 & 44 special, and maybe 30-30 and one other rifle caliber. What other rifle caliber would be not sure, probably 243 Win or 6.5CM or possibly 30-06 (I've wanted a Garand for a long time).
Not planning to cast bullets myself, and would be fine with jacketed bullets as long as it's still cheaper than buying factory practice ammo.