I have been trying to recall what were the biggest problems I had with the GP-100s I had before I basically exited the revolver world. This is more or less in numerical order and does not include stuff so out of spec to begin with that required a trip back to the factory (like b/c gap issues). Despite potential pitfalls, I still would much prefer self-smithing a Ruger DA to trying to cure a S&W on my own. YMMV.
1. Pieces of debris in the guns was easily number one. I learned that I had to disassemble any new Ruger DA and clean them thoroughly, because there was ALWAYS at least one significant piece of metal somewhere, even when the gun seemed normal. Foreign object removal was what spurred me to get Iowegian's Book of Knowledge (IBOK) for the GP-100 and maybe save myself from making things worse. (I can always make things worse.) It was a great resource but is hard to find today.
2. The hole in the trigger guard assembly for the trigger link plunger/trigger guard latch spring/trigger guard latch was a multiple offender. Burrs and/or crap making the trigger action inconsistent. If there was a stage in the process of making a GP-100 where a cutter or bit went to die, this was the place. "Change my mind," as Crowder says.
3. Either the pawl or the ratchet having a burr. If it was the pawl, the problem was consistent; if the ratchet, different chambers were affected.
4. Transfer bar not freely sliding/pivoting.
5. Burr on the hammer or grit at the hammer/hammer strut interface. (Here I will mention that the self-inflicted issue of a hammer strut or mainspring seat flipped around can also be embarrassing).
6. Burr/machine mark on the cylinder latch where it would rub on the cylinder before lock-up. This is one that surprised me.
Time for a confession: I still consider DA revolver service to be sort of an art form compared to work on SA revolvers or (most) semiautomatics.