I was pretty excited about the new crop of 10mm pistols but my hopes are fading. Somewhere I read that the M&P 2.0 was designed with heavier bullets in mind but I can't verify the truth of it. Right now it's new enough that I've found no credible sources that can verify reliability with 200gr or larger bullets. Since I actually do rely on a sidearm for protection from Grizzlies my main criterion would be the ability to run reliably with heavy hard cast. There are few places in the CONUS with more big bears than my corner of SW Montana, not far from Jellystone. At my previous job here you pretty had to carry bear spray to walk the grounds of the property, and we kept a stack of cans in the kitchen. My P30 runs 200gr Underwood perfectly, and I don't think just launching a 180gr a little harder is enough of an improvement to bother. Ultimately I might just go with a .44 Mag and call it good. FWIW, once I get to where I'm camping the Beretta 1301 Tactical loaded up with Green Lightning takes over as primary.
Still, if the code has finally been cracked and there's a striker 10mm that will run 200gr ammo reliably I'd love to get one! And it can be a one trick pony, I'm okay with giving up reliability with lighter stuff to get dependable performance with heavy bullets. I've got plenty of other sidearms for CCW.