I am no physicist but every rxn = equal/opposite rxn.
Between limitations of barrel length and acceptable recoil characteristics in an actual (not just ATF defined) pistol I don't think we will get rifle like injuries from a handgun. Just sort of the worst of both worlds.
maybe I'll be proven wrong. Just not sure how you can get away from the recoil/energy required to propel a cartridge fast enough to do so. but again, not a physicist nor an engineer.