Lots of caveats with this kind of thing, but here goes.
My wife will sometimes use an SR22 loaded with CCI Mini-Mags. Paraphrasing Mark Twain, "it might take the whole magazine to make a full dose for a dirtbag," but she can make a tighter, faster ten-round group up to 25 feet with that little plinker than anything else she has EVER shot. It fits her, and she can manipulate it.
I can't coerce her past a certain point, so I grit my teeth and keep that thing spotless inside and out.