I'm trying to reach the end of a years long search for my ideal mid-size or full-size primary carry revolver for IWB carry, in lieu of a semi-auto for times when I decide I want to. As discussed before, I'm looking for the most durable, reliable, and effective service-sized revolver for this role. Primary contenders are a 4" stainless Ruger GP100, a 4" Stainless S&W 686, or a S&W Model 25/625 (in either .45 Colt or .45 Auto).
Leaning towards the Ruger, although QC complaints I've seen and heard make me hesitant. For S&W, I've always been wary of the stories of internal locks activating, as @DocGKR has seen on police armorer work benches (granted, these were J Frames IIRC). I like the idea of a .45 Colt Model 25, but even with lots of primers and .452" projectiles, it's not as practical to shoot a lot of that caliber compared to .357/.38, but I've always liked big bore bullets going at moderate velocities.
My brain is telling me the GP100 is the most practical and viable answer, but my QC concerns and affection for .45 has me looking at the other choices. I was hoping to get some insight from those here who are more familiar with, and carry, revolvers more than I.
Provided I take good care of it, use good ammo, and use a toothbrush under the ejector star at extended shooting sessions, would the GP100 be the most reliable and durable long term option? Or am I overlooking something?