Originally Posted by
SwampDweller
OP's subject is something I've been wondering about as well. It sure seems like the gun would last forever using .45 ACP or moderate .45 Colt loads. Only question is, are there any .45ACP/.45 Colt JHP loads that would be able to expand out of a 2.5" barrel? The velocities you cite above, are those chrono'd from the Alaskan?
Then again, even if no expansion is attainable, a moderate .45 Colt or .45 ACP full wadcutter would probably be pretty effective on it's own.