I put close to 10K through my 16's, never bothered me at all. I could see it being different for everyone though depending on stock extension, stance (squared up vs. bladed), and other factors affecting head position.
Might be worth breaking the edges with a file or sandpaper. I do the mildest of undercuts to my Glocks, not even noticeable from a side profile view but smoothing the edge of the trigger guard makes all the difference in the world to my knuckle. Perhaps a small change could lead to a noticeable improvement here too.