It is not just a matter of aligning the weapon with the forearm bones, but steering that recoil energy in a direction that does the least damage. Depending upon the power of the cartridge, that can be significant. That which is probably OK with 9mm might not be so much OK with more powerful weapon.
My layman’s take-away is that a two-handed grip, with the forearms relatively symmetrical, should, indeed, help mitigate the effects of a imperfect grip. My big-city LEO’s take-away is that my support hand almost always has other things to be doing, at the moment one may have to react to a sudden threat, so, one-handed shooting MUST be thoroughly trained. Being retired from LEO-ing has not changed that perspective, with such things as pre-school/pre-K grandsons, slow-moving elderly relatives, and leashed dogs* being frequent factors. One-handed training is necessary; two-handed training is a nice luxury. My humble, but informed opinion.
To be clear, I am not any kind of expert.
*I do not consider a leashed dog to be a line of defense. I may let my GSD cover my/our retreat, but do not want her getting into my bullets’ paths.