Hey man, good to see you! Congrats on making GM in PCC too. I'm kind of going down that rabbit hole. It's fun to learn new systems. I want to see you GM revolver and see people's faces when you win a National Championship in that!
Some possible considerations to your counterpoints:
PCC versus handgun and HHFs: No turn draws for PCC and no "strong hand only" either affects HHF. Also, HHF has fudge factor built in. Production and CO have same HHFs for most things and CO is easier to shoot for most. Single stack minor (10 round capacity) has easier HHFs than Production as well....
Which brings us to the next point: Shooting one handed and having one hand / arm free to do something else in a HD scenario (like open doors, carry a small child, talk to police on a cell phone, etc). So potentially practical reasons at the expense of speed and performance.
And other esoteric things like ballistics and defeating body armor if the attackers were so equipped. Because if you didn't care about ballistics and were just talking about less concussion and lower flash... then we'd all have 22LR home defense weapons, no?
I'm not an Operator and am just a middle aged gamer, so I only shot a suppressed 223 indoors for the first time last month.
But I was super pleased at how nice (non-flashy, non-concussive) it was in no-light conditions even shooting regular (non-flash reduced) ammo was with the suppressor.
Would love it if you posted / elaborated on your overall PCC gaming thoughts for gaming. Is it more "fun" than CO or are you finding the "fun" in learning a new platform / weapon system?