Handloading reversed WC was the hot thing when I was a kid reading gun magazines in the 1970s and early 1980s. However like a lot of the "gun lore" from those days it was bad advice.
"back in the day" it was thought getting hollow points to open up inside the body was the key to effectiveness. My Agency was issuing 110 grain .357 magnum JHPs into the 1990s on the same theory. And.. we were wrong.
Those type loads expand prematurely and create ineffective wounds. They fail to penetrate the 12" to 18" necessary to reach the vital structures inside the body which result in stopping threats.
Not to mention use of handloads in a self defense situation can create other issues.