I agree that a $2,000 1006 isn't a good idea. I'm just not sure I agree it would have to cost $2,000; the presence of Sig Legions, Springfield SA-35s/Mil-Specs, SW1911s, CZ-97s, Beretta 92Xs and others at far below that suggests, to me, it could be done for less.
I feel the 10mm is an "aspirational" caliber in search of a gun with a soul. I just don't think a plastic M&P is that gun. And if you really need a 10mm for the back country, more utilitarian options already exist. But hey... maybe I'm wrong and the thing will sell like crazy.
All that said...
A steel-framed M&P (a la Sig AXG & Walther Q4 SF) in 10mm would get me excited.