I took the new 22 Gen 5 out today and shot it against my 22 Gen 4. I was just shooting steel plate racks to get a feel for the Gen 5 and break it in. I ran about 150 rounds through each with 180 grain Blazer Brass and 180 grain Winchester. The 22 Gen 4 had much more recoil and the 22 Gen 5 was much quicker back on the plates. I felt like I was shooting a 9mm, the recoil was less and the muzzle climb was less. The Gen 5 felt like a gentle push and as if the ammunition was under powered.
Overall I like it a lot. Much like the 23Gen 5 I think Glock did well increasing the slide mass on the Gen 5 .40's. I am keeping an eye out for the Gen 5 35.