For 38 Special I had very good luck with a GT Bullets 160gr LSWCHP loaded with 5.3gr of Unique. This load runs 850fps from a 2" LCR and worked quite well in gel from what I remember.
Those who aren't too concerned about hand loads and self defense might be well served with this combination.
I suppose ideally a person would tailor the load to 850ish out of whatever barrel. Possibly 5gr flat for a 3" barrel and maybe 4.5gr from a 4 inch?
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