It's just money.
But seriously, if you're putting that kind of money into this gun I suggest going that extra step and upgrade the irons. There's no practical gain to eliminating the rear dovetail and moving the RMR back that little bit.
I'm strongly dedicated to the idea of back up iron sights on a red dot equipped pistol for two reasons:
1. Yeah, in the unlikely case of the optic failing due to internal problems/damage/battery fail. Possible, but increasingly unlikely. I finally changed out the battery on a Type 1 RME after nearly five years. It was on auto adjust most of the time, and in my carry bag or under a shirt. Pretty impressive, though I would recommend yearly battery change out. That was my first RMR and an experiment.
2. Also 'cuz -- for me -- using the irons to index on and get that dot was a huge help to helping train my little monkey brain.
I've been shooting RMR'd Glocks for about five years and now I rarely use the irons, but on days I stumble they help me out. Most have at least a front tritium; my daily carry -- a G43 -- has both front and rear, just in case.
Also, to bust the myth, the Ameriglo suppressor height sights DO work on the G48 Brownells slide I have. There is very little room to adjust windage, but it's enough to zero the gun. See attached pix. Both the G48 and G43 have full size suppressor height sights. The G43's sights are MOS height 'cuz mounting a full-sized RMR required a cantilevered or tapered adapter plate and that adds to the height of the sight axis. It looks a bit weird, but it's a laser ... a teeny, tiny laser. Shoots way better than I'm capable, so I'm okay with it.
Aaron at Sage Dynamics did a find job 'splaining a lot about the RMRcc. It doesn't turn me on, but YMMV.
I'm gonna do one more, a factory G48X -- if I can find one -- and send it off to accept a Holosun 407K. Then I'm gonna stop before my wife files a cease and desist order.
Just my dos centavos.