Now to be clear, (‘cause I don’t want people to misunderstand that what I’m saying is testing is junk science and should be ignored), I too once worshipped at the altar of ballistic gel. It has its uses. Mostly good for killing time when you cannot otherwise be shooting, or between wars, whatever. But an inordinate amount of time gets spent wrapped up in concerning oneself in minutiae that you do not need to concern yourself when it comes to shooting for all the marbles. A miss is a miss. Bad guys don’t care what ballistic gel studies showed. They often times don’t give a fuck about marginal hits either. One thing that cannot be argued, is that bad guys respect well placed shots, because they don’t have a choice in the matter.
Even then, there is nothing in the Bible of Ballistics that says an asshole will stop being an asshole with one well placed shot. Pick a round that works in your gun, is reasonably accurate (Sub-MOA/minute of asshole is sufficient), and you can shoot enough of to become proficient. Graveyards have been built for the people killed with supposedly shit ball military ammo. I’m confident that if you brain someone with any high powered rifle, your troubles with that person will be over rather quickly.