Bro, you're trying to have a 1990's discussion on ballistics.I don't even own a .45 handgun at the moment (just .380, 9mm's, and a .357 SIG), but I do tend to shoot 45 more accurately than 9mm (and even slightly more so than even .357 SIG). From what I've seen, real world data documenting shootings tends to support this (https://www.buckeyefirearms.org/alte...stopping-power).
That said, there is something to be said about "practical accuracy". I would even argue a little dispersion is better than keyholing someone as that second and third bullet might pass right through an attacker's body dumping most of its energy (not that keyholing is likely in a self-defense situation). In fact, even though the data I've seen shows .45 ACP was significantly more accurate, it was NOT more effective (or at least only marginally so). For example, 9mm's ability to incapacitate was a point higher, but that was certainly within the margin of error pertaining to its potential for failing to incapacitate someone. As such, the superior accuracy on average does not offer much of a tactical advantage (though it might make up for the less than impressive wound channel of the slower .45 projectile).
That said, .45 ACP is typically subsonic, so it also makes for a great suppressor host (because it doesn't rely as much on velocity to create energy). When 9mm is subsonic it is going to lose a lot of ft. lbs. of energy.