I'm no doctor but, maybe something related to this:
https://handcare.assh.org/Anatomy/De...ded-Wrist-Pain
For me, I ended up having a cyst right in between the Ulna, Radius, and Lunate bones. Irritating as hell, and when it flared up bad, it felt like my wrist was fractured. Still recovering from the surgery and don't have full range of motion, but getting there.
You know, now that I think about it, I think I experienced a little bit of similar pain after shooting my G48. I love the gun, the size, etc. Though, I'm finding a larger circumference grip tends to feel less fatiguing to me. In my case, and with this gun or Glocks in general, I think it makes sense why. Because of the grip angle, you generally have to cam your wrist downward more. I believe that means the Ulna, Lunate, and maybe a few other bones would be coming closer together.