When I run a white light and a grip laser I don’t use all them at the same time. When my trigger finger is indexed on the slide and my grip has activated my crimson trace grip laser the laser is blocked by my finger (I am right handed) .
In low light the laser dot is very visible on the target (once I move my finger) . When the white light is on in lowlight the sights are silhouetted and very visible. If you cannot see the sights clearly use the white light is to illuminate and identify the threat/ target; turn light off - use the laser and target focus to aim .