My opinion is the worst thing that the vaccine will do is not work. Also, with mass vaccinations, will we see folks being less careful with unfortunate results?
My opinion is the worst thing that the vaccine will do is not work. Also, with mass vaccinations, will we see folks being less careful with unfortunate results?
https://en.wikipedia.org/wiki/Peter_HotezOriginally Posted by vcdgrips
This is the first mRNA vaccine ever used on humans, and the timeline has been accelerated due to the severity of the situation.
This is fairly easy to discover based on the typical timeline of developing a vaccine vs. the current timeline. People involved in the creation/research and administration of virus vaccines tend to be very conservative due to the history involved and the adverse effects previous failures have had on the adoption of vaccines worldwide. I haven't found anyone that works in those fields that feel this timeline is ideal, they just feel the rush is justified due to the situation. They understand the concerns and have them themselves. I don't think attempting to whitewash that is doing anyone any favors.
Not trying to be argumentative. I'm way outside my lane and don't know much here.
If antibodies/immunity that result from getting and successfully fighting off the virus last only a few months, how do we expect the vaccine to be effective for much longer than that?
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Not another dime.
This happened at my hospital
https://www.nbcnews.com/news/us-news...rkers-n1248255
Doesn't read posts longer than two paragraphs.
Awesome story!
Thats just too cool for words. Glad to hear he's out and expected to make a full recovery.
Lots of well intended speculation here. My general feeling is the COVID vaccine will play out pretty smooth, especially based on the stakes involved.
I have done public health work for just shy of 20 years and was involved in one of the 2009 pandemic vaccine trials. During that time, I have not seen anything comparative to the present vaccine ground game. The logistics planning is much higher and the level of data tracking (to provide post vaccination safety and general accountability) is unprecedented. As an example, there was a federal assessment completed in September on the -80C freezers and CO2 production supply chain necessary for the Pfizer. There are almost no issues found and those were addressed with compensating controls. There is also detailed OJT training and supporting materials such as PPE to be provided with each shipment dispatched.
Getting into details doesn’t really add more - my opinion is the planning is more than adequate and not the long tent pole. The production is reportedly solid, but my knowledge is limited (and no doubt there are heroic efforts being made). The safety authorization is underway for the first vaccine, but several others in the pipeline.
I do think the present non-transition process is fly in the ointment. Some of the associated decision making seems to have stalled out. Not intended to be more political than observation that three weeks of non decisions and deferrals cannot be good for America.
These are all open questions, but one of the talking points in every grant application written for vaccine development is the need to find ways to elicit more durable immunity.
Scott Halstead is the guy who discovered antibody dependent enhancement and did a ton of work on Dengue. He's quite elderly now but still somewhat active. A few years ago he spared 30 minutes for a phone call with me. One thing he said that really stuck with me is that "vaccines are fueled by hope." Truer words never spoken, especially now!
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I'm 58 and very healthy, and I would have taken any of the major vaccines stil in Phase 3 yesterday if possible.
Certainly being a beta tester/early adopter is not ideal, but IMO in this case and at this point of development "perfect is the enemy of good".
My wife just called informed me during her shift last night she spent aprox 1.5 hrs with a patient before discovering she had covid. This is gonna b interesting.
I'll wager you a PF dollar™ 😎
The lunatics are running the asylum
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