Super 8s allow dogs, Ive stayed at them for many years.
I stop every couple hours to walk the dogs at rest stops or other places that are good. It helps me also, I get seized up sitting for long.
Keep your vehicle doors LOCKED when getting gas, even when you are standing next to it filling the tank. I even do when someone else is in the vehicle. One scam is to open a door on the other side and grab anything not nailed down, most people never notice it happening.
Get a spare chipped key if you dont have one, its cheaper to do now than when you lose one on the road. Spare unchipped keys can also open doors and let you roll windows up or down but wont start the vehicle. If you have a door remote, not having it on the key will help prevent locking the key in the vehicle. Same with the unchipped key. I dont leave any other keys on the vehicle key, if the vehicle is jacked, Im not giving them anything else that may be useful, that includes not leaving insurance and registration in the vehicle, only in my wallet.
I keep a small bowl in the rear door pocket/drink holder spot along with bottled water for the dog. More water bottles elsewhere (20 oz gatorade or soda bottles work well) and refill at motels as needed rather than carrying a case of bottled water, though having lots of water in the summer is a good idea in case of a breakdown. I also keep spare leashes by each vehicle door so i can grab one no matter where I need to get the dog out from.
It can be tough in the summer to keep dogs cool. Its not legal in some states to leave a vehicle run when not in it, and an invitation to get it stolen. I ended up putting a window AC unit in mine for summer travel and a small generator in the rear cargo box. Having another person to sit in the vehicle when going to the bathroom is nice, but I usually dont, so the AC and gen works OK. Same for getting food. Heat can build up very quickly. I used to take a white sheet to put over my truck to help keep it cool, it helped, but I havent used it in a while. Still take it in case of a breakdown. Parking so the sun is directly behind helps some also, but isnt always an option.
Parking where you can see the vehicle, and getting seats in restaurants where you can easily see it is also good. I always ask, they usually will accommodate that.