I bought a used P220 that had apparently been a police trade-in. It came with a nicely broken in (burnished rails, etc.) slide and barrel paired with what appeared to be a brand new frame. As I was cleaning it, I realized that the barrel hood was an interference fit in the slide due to a machining defect in the slide, and slide material was galling onto the hood. I was able to clean up both parts and correct the issue. I realized that the interference fit was causing excess force to be required for the slide to go into battery, and that the only place that force could be reacted through was the slide rails. Took extra care fitting everything so the slide could be cycled manually without the recoil spring without undue force - everything just having a nice slip fit as it went into battery. It's a pretty nice pistol now.
I believe that lockup tolerance stack is a likely, if not primary, cause of variation in rate and extent and the oft-reported self-limiting characteristic of initial rail wear on classic Sigs. Once the rails wear enough to relieve the interference out of the system, it stops. It may happen with virtually no wear, it may take a few hundred or a few thousand rounds, it may be that the frame becomes unserviceable/unrepairable before it gets there.
I will check that on any classic Sig pistol I ever put into service, before rounds go through it.
Also, check the rear corners of the slide for burrs on/around the rails. Most of them have some burr that will tear up the very back of the frame if it's not corrected, which is easily accomplished with a wedge/"knife" type stone or jeweler's file. Can be an issue on any brand of pistol with continuous slide rails on the frame, FWIW. Just to beat my usual dead horse, I've seen a NIB S&W semi with such bad burrs on the slide that it had significantly impacted the anodizing the length of the rails.
Someone has reported here previously that an agency in TX had a whole batch of classic Sigs returned because the machined surface on the rails of the slides chewed up the rails on the frames with low round counts.
All that is IMO, based on my own investigation of just a couple of samples and using it to interpret the many and varied reports I've read on the internets. So treat it as if it's worth exactly what you paid me for it.