With mine one is set up for 45 and the other I use for 9/40...(one for large & one for small primers). I really liked my 550 and think it’s easier to use when you’re starting out but there is no comparison to a kitted out 650 for cranking out ammo. I loaded yesterday and after a couple hours I had 1k 45, a couple hundred 9, refilled 20 primer tubes, restocked my bench and cleaned up.