Good point. That said personally I would just make a heavier gun like the 442 work for around the house if I decided I was tired of pocket carrying my G26.
As for an "everywhere" handgun I personally find all j frames big for that role and in the past have defaulted to things like the Kahr P380 after vetting it. I really think it and the P32 have made the small .22 autos obsolete if you find a good one.