Sure...but OP talking about 10-yard groups not 5.
A POI five inches to the right at 10 yards works out to be less than one degree of bore deflection. With a 5" sight radius, that means that the front sight is 0.07" off true center, or just over half the width of most typical front sights. So if the sights are not perfectly aligned for POA=POI, small differences in perceived sight pictures could add up at this distance