The first rule of gunfighting still applies--I'd rather have a .380 than no gun...
In the past, lot's of .380 pistols have had reliability and functional issues, especially after being carried in a pocket full of lint or on an ankle--in those scenarios, a lightweight J-frame was a better option.
For a dedicated BUG and for folks that cannot handle the recoil or operation of .38 or 9 mm, a G42 shooting ball (including Lehigh XP) is acceptable; a poorly expanding .380 JHP like XTP or Hydra Shok will also work.