I don't have a 650, but I do have a RL1050 with a Mr Bullet Feeder and a 550. The 1050 is usually set up for 9mm. The 550 is used for various other lower usage calibers. It is set up for .45 ACP right now. Loading primer tubes etc. all take the same time no matter which press you have.
I started each test with primer tubes loaded and bullets, cases etc loaded in feeders etc. 100 rounds of 9mm on the 1050 took 4 minutes and 18 seconds. 100 rounds on the 550 took 10 minutes and 58 seconds. This is at a somewhat leisurely pace.
I will usually load for about 30 minutes at a time and take a break. I can get 500 rounds easily on the 1050 or 200 rounds on the 550. I have had both presses for a long time.