In terms of defensive use, there is an issue with many of the 9mm carbines, in reliably and quickly getting them loaded. Watch a USPSA stage with an unloaded start, and there is often drama, between magazines not getting seated and falling out, and/or stoppages caused by manual cycling the first round having less velocity than the bolt stripping a round when firing. I just don't see those issues with a 5.56 AR.