I took a couple extra minutes setting it up(ground the bolt head flat and set it up with a spent case) and haven't had any problems with seating primers in many, many thousand rounds. With the exception of getting some small primer .45 cases mixed in with the real stuff, I've never had any kind of priming issue at all o the load master. I can't say that with the Pro1000 which is the primary reason I went to the Load Master, that and I wanted a five station press.
I do run a decaping die in station 1 and resize in station two to center the case for priming.