I've been back and forth on this issue a ton of times. In the end, I sold the G43. In fact, right now, for ease of cross-country movement, the ONLY Glock I own is a G26. For daily carry at work, I carry it with a +2 magazine, with a G17 +2 as a reload. Off duty IWB, I use a flat base mag with the same G17 +2 as a reload. For me, the debate is G26 or P365, and the P365 is HANDS DOWN smaller and lighter, and "feels better" in my hand (in fact, it makes the G26 look and feel positively HYUGE). But the G26 is easier to shoot on low probability targets, and I can reload with a "real" magazine, so, in the end, my profession tells me the G26 is the better "one gun" solution right now.
I say all of the above in light of the fact that, for the last 10 years or so, my "one gun" solution has always been a G19 as default. A combination of events has led me to not have one right now, but I'll be remedying that shortfall ASAP once my PCS is complete. Likewise, the potential future viability of a G43X or G48 with a 15 round metal magazine could change things up completely.