The appeal of 10mm is that it might offer enough more velocity to penetrate certain things, like an animal's skull, that a regular service caliber would not. Those things, like a skull, having a minimum velocity threshold for penetration, that effectively turns the bullet into a pass/fail exercise.
There are two related issues. One issue is whether that load will function reliably in a semi-auto, because if it won't function reliably, the stoppage sort of negates the capacity advantage of the 10mm in a pistol. The second issue being whether the bullet is designed as a penetrator load, and will perform with enough penetration to penetrate the skull. A subset of number two, is who makes that penetrating load, and is their quality such that you would reasonably be able to rely on it.