The cam block locks the barrel in position and under recoil rotates it. Here's an article from the late Stephen A. Camp http://www.hipowersandhandguns.com/s...x4_storm_9.htm
Ernest Langdon has commented in his Compact PX4 thread, the frame seems to take very little stress as it is all focused in the slide. I suspect the cam block is the part absorbing most of the stress.