I think (but haven't done any kind of study on this) that some of the MPX problems lie with ammo, and people not understanding the MPX. For Prod/CO guns, or blowback PCCs, a lighter powder charge is going to shoot softer. Putting this super soft ammo in the MPX is not the best idea. The MPX is gas operated. It needs gas to run. It likes more gas. More gas gives you more of an operating margin. In that respect, it's more like an open gun. Of course, SIG hasn't helped anything with their perpetual rolling changes.
Things I would keep an eye on are the extractor parts (have spares of that spring/o-ring) and keep the piston/gas expansion chamber clean. Oh, and oil the carrier.