Lol.
No, not much difference at all. One of the most essential points in shooting accurately on the gentle run like that is to avoid letting the visual chaos that will be inherent to that amount of movement goad me into accepting less visual reference than usual. Visual reference is going to be less precise because of an aggravated wobble zone, but I still want the most precise visual reference I can get. I still use a sight picture composed of target, front sight, and rear sight, there's just more movement in it.
It can be tempting to aim using the slide silhouette or similar, and that can work, but I think it's less precise and I don't think it costs me anything to use the more precise sights instead.
Technical excellence supports tactical preparedness
Lord of the Food Court
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