Originally Posted by
pangloss
Your question wasn't directed at me, but there is no data available to support any answer. In other words, there's no way to know what would be optimal. A lot of people at work, myself included, were immunized in Jan/Dec. We started seeing breakthrough cases in July (six months after the second dose of vaccine). On average, people in my small cohort have lost 90% of their antibody between March and July/August. We're finally starting to generate some T cell data, and that doesn't look encouraging either. If you have a lot of community transmission in your area, I think the best decision would be to get the boost at six months instead of eight months. I don't know of any data from any system, that says there would be a difference in response to vaccination resulting from this sort of interval change. Testing differences like this would be expensive and likely not provide much useful information.