I'll quote my best friend who has a extensive background in doing very bad things to lots of very bad people.
"I like to carry a Glock and fight with a 1911." Sums it up pretty well.
I actually have this pretty well figured out these days.
Service guns
9mm-Glock 17, 19, or 17 chopped for 19 mags.
.45ACP-HK45C
Enthusist Guns
9mm-Hk P7
.45ACP-1911
Outdoors stuff-Big Bore revolver
Everything else is pride of ownership at this point.