I tried the Hornady Critical Duty 135gr .357 rounds through my M65 3" this weekend with dismal results. It did not like this ammo at all. Terrible groups! Recoil was more than what I had anticipated. Manageable with some practice I suppose.
I am going to stick with the Speer GD 135gr +P 38 Special round in this pistol. Tight groups, very manageable recoil and a record of decent terminal performance.