I had a Sig P320 RXP with Romeo1 Pro Optic on it, great for shooting without my glasses on.... but when I wore my glasses the flur of the red dot happened and nothing would help refine that red dot like it should be. I tried the pistol without and hated those co-witness sights. sold it.
My Sig P226r Extreme and Ruger LC9s both just have iron sights... K.I.S.S. method works best for myself.
My EDC is a revolver though.