No. The FBI protocol test tests against bare gel, which simulates an "Average" of all tissue densities (which has proven very accurate over 25 years), 4-layer denim added to the bare gel which simulates heavy clothing, Plywood, Wall board, and spaced steel sheets simulating a car door, utilizing 12-14ga steel.Is it standard to test rounds in gelatin with a simulated sternum or other objects simulating bone in place?
Bare gel profiles temporary cavitation and "best possible" penetration and expansion with no hard barrier interruption. The others simulate other possible barrier penetration mediums.
Bones themselves are not typically considered as for the round to be considered effective for Law Enforcement use (and by extension, self defense use) the round must show adequate penetration and expansion through all barriers listed above, and the presumption is that if it penetrates adequately and expands after 1/2" plywood, wall board, or other hard barriers, it will typically handle bone.
When considering the penetration of bone, too, one of the major criteria of bullet design is that it is blunt enough that it will crush bone if it strikes, rather than glance off. With round-nosed projectiles, unless an ideal center placement is achieved, the round profile will cause the bullet to glance off and do little to no damage to the bone comparative to flatter meplats which will have greater effect on bone even with more marginal shots than ideal center placement. There will of course be a point at which the bullet is striking along a radial surface to such a degree that not enough flat portion of the nose will strike the bone and cause damage but will rather simply slide and deflect.
Typical "center of mass" targets will actually place shots just at or below sternum level, which present little bone tissue interruptions, but neither do they avail themselves to quick incapacitation as in the sub-sternum region lie liver, kidneys, stomach, intestines, and other organs which, while certainly important and capable of profuse bleeding, will not be as damaging to the subject's effectiveness as shots to the upper center of mass, between sternum and collar bone, illustrated below:
As you can see, a strike to typical "center of mass" is only going to produce a possible shot to the lower quarter of the heart, presuming size of organ to scale.
Further to-scale diagrams show the rib structure and other internal organ placement, suggesting that the heart, with typical center of mass placement, will not be exposed.
Thus, it is my opinion that utilization of rounds that prove themselves capable of penetration of hard barriers are ideal, and likewise an upper-center-mass shot placement, allowing for greater possible impacts to major Cardiovascular and Pulmonary structures.
Edit: I am not a medical professional, so exact anatomy and physiological minutiae may be inaccurate on my part. However, I did stay at a holiday inn express last night.